Committed to Quality

LRC Hamilton and HRLMP are committed to providing high quality laboratory results for our clients.
As one of the largest integrated laboratory medicine programs in Canada we strive to produce the right results the first time on every sample we receive.
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Test Name:
 		QF-PCR for Rapid Aneuploid Detection (RAD)
Alternate Name(s): Aneuploidy testing, maternal cell contamination studies
Requisition Form: Download Requisition Form
Specimen Requirement: PRENATAL:
Aneuploidy testing (QF-PCR and karyotype) or Aneuploidy and copy number testing (QF-PCR and karyotype/chromosomal microarray, as indicated):
- Minimum 15mL amniotic fluid (>17 mL preferable) or 10 mg chorionic villi AND 2-4 mL EDTA maternal peripheral blood (to be included with all prenatal specimens).

PERINATAL:
QF-PCR or QF-PCR/chromosomal microarray, as indicated:
- 1.5 cm fetal or placental* tissue in sterile transport media AND 2-4 mL EDTA maternal peripheral blood, if possible. (*note: microarray will not be performed using placental tissue)

NEONATAL/INFANT:
Aneuploidy testing (QF-PCR and Karyotype, if indicated):
- 1-2 mL EDTA peripheral blood AND 1-2 mL Sodium Heparin peripheral blood. NOTE: if only one collection tube is possible, EDTA is preferred.

Maternal cell contamination studies (to complement aneuploidy testing of prenatal , perinatal or cord blood specimens):
- 2.4 mL EDTA peripheral blood
Turnaround Time: Perinatal Samples, 8 weeks.
Additional Information: Mothers blood is used to rule out maternal cell contamination.

For any inquiries, please contact geneticsmailbox@hhsc.ca
Method of Analysis: QF - PCR
Test was Last Updated: 4/10/2024
Testing Laboratory: Clinical Genetics
Testing Site: JHCC