LRC Test Information

A Service of the Hamilton Regional Laboratory

Laboratory Test Information

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The HRLMP is committed to providing high quality laboratory results for our clients.
As one of the largest integrated laboratory medicine programs in Canada we strive to produce the right results the first time on every sample we receive.

Test Name:	Endometrial Solid Tumour Genetic Testing
Alternate Name(s):	POLE Mutation analysis, somatic cancer
Requisition Form:	Download requisition form for: R_FINAL_Fillable_Cancer Genetics Solid Tumour_requisition_Jan2025.pdf
Specimen Requirement:	Five unstained slides (5-10 uM thickness) on non-coated, uncharged slides. An H&E slide, with region of interest circled by pathologist, must accompany the unstained slides. Email geneticsurgentreques@hhsc.ca with inquiries.
Turnaround Time:	14 days from receipt in laboratory
Additional Information:	Reflex testing on newly diagnosed tumours with invasive endometrial carcinoma. Genes analyzed: POLE, CTNNB1, KRAS, PIK3CA, PTEN, TP53. For any inquiries, please contact geneticsmailbox@hhsc.ca
Method of Analysis:	Next-Generation Sequencing
Test was Last Updated:	2/25/2026
Testing Laboratory:	Clinical Genetics
Testing Site:	JHCC

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