A Service of the Hamilton Regional Laboratory
Laboratory Test Information
Committed to Quality
The HRLMP is committed to providing high quality laboratory results for our clients.
As one of the largest integrated laboratory medicine programs in Canada we strive to produce the right results the first time on every sample we receive.
Test Name:
Breast Cancer Solid Tumour - PIK3CA Genetic Testing
Alternate Name(s): PIK3CA directed therapy, somatic cancer
Requisition Form: Download requisition form for: R_FINAL_Fillable_Cancer Genetics Solid Tumour_requisition_Jan2025.pdf
Specimen Requirement: Two tubes of curls (5 curls 5-10 uM thickness per tube) if macrodissection is not required.
OR Ten unstained slides (7 uM thickness) along with H&E slide (with region of interest circled by pathologist) if macrodissection is required.
If only one tube of curls or five slides are received, DNA panel will be performed by default, unless RNA panel is specifically requested.
Email geneticsurgentreques@hhsc.ca with inquiries.
Turnaround Time: 14 days from receipt in Genetics Laboratory
Additional Information: Testing on advanced/metastatic breast cancer where PIK3CA directed therapy is being considered.

Genes analyzed: PIK3CA, ESR1

For any inquires, please contact geneticsmailbox@hhsc.ca.
Method of Analysis: Next-Generation Sequencing
Test was Last Updated: 1/17/2025
Testing Laboratory: Clinical Genetics
Testing Site: JHCC